Novel protein – Cytoplasmic fibrils

This entry is about a novel protein that has been discovered and it’s ability to ‘create’ cytoplasmic fibers in insects infected by Entomopoxvirus.

I assume, that this novel protein is p10 and FALPE.

If you look at the construction of Cytoplasmic fibrils you will see a significant match to the fibers related to Morgellons Disease.

To start with, here is an image:



A novel protein which is expressed at high levels in insect cells infected with Amsacta moorei entomopoxvirus was identified by our laboratory.

Immunofluorescence and immunoelectron microscopy techniques revealed that this protein is associated with large cytoplasmic fibrils which accumulate in the cytoplasm between 96 and 120 h postinfection.

We subsequently called this viral polypeptide filament-associated late protein of entomopoxvirus.

The fibrils containing this polypeptide are closely associated with occlusion bodies and may play a role in their morphogenesis and maturation.

Here an image: 

‘exploding’ Baculovirus occlusion body  image


I found interesting,  that not only the Baculovirus has the characteristic of forming occlusions bodies but also the Entomopoxvirus.

The forming of occlusion bodies or Polyhydra is a significant feature of many skin, debris or specimen samples microscopically examined.

We postulate that BOTH insect viruses, Baculo- AND Entomopoxvirus are the main vector causing Morgellons Disease.

~ by k&k on September 7, 2009.

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